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PECULIARITIES OF ENDOMETRIAL STATE OF THE PATIENTS WITH ABNORMAL UTERINE BLEEDING

Abstract

Abnormal uterine bleeding (AUB) is one of the main clinical symptoms of the diseases of female internal reproductive organs. AUB cannot be considered as the specific symptom of a particular disease. To know the causes of AUB is necessary for rational treatment strategy. Aim. to study the peculiarities of endometrial state of the patients suffering from AUB and the combination of different forms of pathological endometrial (E) changes on the background of AUB. Material. the results of histological examination of endometrium (E) samples taken from 688 patients. Results. the structure of pathological changes of endometrium in case of AUB was identified. Conclusion. complex endometrial hyperplasia and atypical endometrial hyperplasia occur without any regularity on the background of various changes of E reflecting the state of both hypo- and hyper-estrogenia.

About the Authors

V. N. Gulieva
State Federal-Funded Educational Institution of Higher Vocational Training I.M. Sechenov First Moscow State Medical University of the Ministry of Health of the Russian Federation
Russian Federation


A. Kh. Bishtavi
Moscow State University of Medicine and Dentistry
Russian Federation


A. Yu. Kostin
Clinical Oncology Dispensary number 1 Department of Health in Moscow
Russian Federation


A. E. Ivanov
Clinical Oncology Dispensary number 1 Department of Health in Moscow
Russian Federation


A. G. Solopova
State Federal-Funded Educational Institution of Higher Vocational Training I.M. Sechenov First Moscow State Medical University of the Ministry of Health of the Russian Federation
Russian Federation


Yu. Yu. Tabakman
Clinical Oncology Dispensary number 1 Department of Health in Moscow
Russian Federation


References

1. Kuznecova I.V. Vozmozhnosti terapii giperplasticheskih processov jendometrija. Trudnyj pacient. 2010; 1-2.

2. Perel'muter V.M. Morfologicheskie izmenenija jendometrija pri giperplazii i jendometrial'noj intrajepitelial'noj neoplazii. Sibirskij onkologicheskij zhurnal, 2008; 5 (29): 5-10.

3. Tabakman Ju.Ju. Rak jendometrija. M. 2009: 32-46.

4. Чепик О.Ф. Морфогенез гиперпластических процессов эндометрия. Практическая онкология. 2004; 5 (1): 9-15.

5. Horn L.C., Schnurrbusch U., Bilek K., Hentschel B., Einenkel J. Risk of progression in complex and atypical endometrial hyperplasia: clinicopathologic analysis in cases with and without progestogen treatment. Int. J. Gynecol. Cancer. 2004 Mar-Apr; 14 (2): 348-53.

6. Kurman R., Kaminski P., Norris H. The behavior of endometrial hyperplasia. A longterm study of “untreated” hyperplasia in 170 patients. Br. J. Cancer. 1985 Jul 15; 56 (2): 403-12.

7. Lacey J.V., Sherman M.E., Rush B.B. Absolute Risk of Endometrial Carcinoma During 20-Year Follow-Up Among Women With Endometrial Hyperplasia. J. Clin. Oncol. 2010 February 10; 28 (5): 788-792.

8. Lacey J.V. Jr., Ioffe O.B., Ronnett B.M. et al. Endometrial carcinoma risk among women diagnosed with endometrial hyperplasia: the 34-year experience in a large health plan. Br. J. Cancer. 2008 Jan 15; 98 (1): 45-53.

9. Terakawa N., Kigawa J., Taketani Y et al. The behavior of endometrial hyperplasia: a prospective study. Endometrial Hyperplasia Study Group. J. Obstet. Gynecol. Res. 1997 Jun; 23 (3): 223-30.

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Review

For citations:


Gulieva V.N., Bishtavi A.Kh., Kostin A.Yu., Ivanov A.E., Solopova A.G., Tabakman Yu.Yu. PECULIARITIES OF ENDOMETRIAL STATE OF THE PATIENTS WITH ABNORMAL UTERINE BLEEDING. Obstetrics, Gynecology and Reproduction. 2014;8(1):12-14. (In Russ.)

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ISSN 2313-7347 (Print)
ISSN 2500-3194 (Online)